Prescription Skincare
Meet GHK-Cu.
In a Cream.
Meet GHK-Cu prescription skincare. No injections. Just a simple topical cream.
Online evaluation with a licensed provider.
Discover GHK-Cu ↓
What is GHK-Cu?
A Different Approach to Skincare.
GHK-Cu is a naturally occurring copper-containing compound found in the body. Neshiva offers a topical prescription cream containing GHK-Cu, available following evaluation by a licensed provider.
Skincare Made Simple.
Topical Application
Applied directly to the skin. No injections needed.
Easy to Incorporate
A cream format that fits into a skincare routine.
Provider-Guided
A licensed provider evaluates whether a prescription is appropriate.
Get Started
Simple, Transparent Pricing.
Start with one month and explore longer supply options when appropriate. Save more when you buy more.
1-Month Supply
$217
$189
Get Your FormulaSave More When You Buy More
Choose a longer supply during your intake for a lower monthly price.
Prescription Skincare
Guided by licensed providers.
Discreet Fulfillment
Delivered to your door, where available and when prescribed.
Flexible Supply Options
Save more when you buy more.
Longer supply options are shown during intake. With a qualifying Neshiva membership, a 3-month supply is $463.50 paid upfront (about $155/month); membership fees are additional. Prescription depends on provider evaluation and approval.
A Simple Process.
- 1
Step 1
Complete Your Online Visit
Answer a few questions about yourself and your skincare needs.
- 2
Step 2
Provider Evaluation
A licensed provider reviews your information.
- 3
Step 3
Prescription If Appropriate
If approved, your prescription is sent for fulfillment.
- 4
Step 4
Home Delivery
Your order is shipped to your address.
The Science, Simplified
Can a Cream Really Penetrate Your Skin?
Yes. And it doesn't have to travel through your pores.
The skin's outer layer acts as a protective barrier, but certain topical ingredients can penetrate it through pathways between skin cells, through skin cells, and through hair follicles.
Scientific research has demonstrated that copper from topical copper-tripeptide preparations can penetrate and remain in human skin under laboratory conditions.
The extent of penetration depends on the ingredient, concentration, and formulation. These findings do not establish how deeply Neshiva's specific GHK-Cu cream penetrates or guarantee particular skincare results.
Explore the Research+
Study 1 — Topical Copper-Tripeptide Penetration
Hostynek et al. (2010)
Laboratory research investigating the penetration and retention of copper from a topical copper-tripeptide preparation in human skin.
View on PubMed ↗Study 2 — The 500 Dalton Rule
Bos & Meinardi (2000)
A foundational scientific paper explaining how molecular size influences passive skin penetration and why the skin barrier matters.
View on PubMed ↗These publications provide general scientific context and do not constitute clinical testing of Neshiva's specific formulation.
Prescription skincare, subject to licensed provider evaluation and approval.
Questions, Answered.
Important: GHK-Cu cream is a compounded prescription product. Compounded drugs are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality. Treatment depends on evaluation by a licensed provider. Individual results vary.
Your Skincare Journey Starts Here.
Explore Neshiva's GHK-Cu cream through a simple online provider evaluation.
Get Your Formula